Immune Tissues

As part of our comprehensive antibody discovery workflow, we offer precision immune tissue preparation from high-titer, immunized mice. Upon confirmation of robust immune responses, we harvest key lymphoid organsβ€”including spleen, lymph nodes, and bone marrowβ€”from each selected animal.

These tissues are enzymatically and mechanically dissociated into high-quality single-cell suspensions. Red blood cells are selectively lysed to enrich for viable immune cell populations. Prepared cells can be:

  • Directly utilized in our hybridoma generation pipeline

  • Preserved in RNAlater for transcriptomic or molecular downstream applications

  • Further processed for custom cell isolations (e.g., B cells, plasma cells) and shipped to client facilities upon request

Our protocols ensure high cell viability, reproducibility, and compatibility with a range of downstream workflows, including sequencing, cell sorting, and functional assays.